Lilly and the cold case team will have to decode the clues given by a twisted killer in order to save the life of a young boy who has been left to die alone. But first they must find the boy and for that they need to dig a little deeper into their own pasts.
- Kathryn Morris as Lilly Rush
- Danny Pino as Scotty Valens
- John Finn as John Stillman
- Jeremy Ratchford as Nick Vera
- Thom Barry as Will Jeffries
- Tracie Thoms as Kat Miller
- Željko Ivanek as John Harding ("John Doe") (2006)
- Anne Gee Byrd as Mrs. Jablonski (2006)
- Tim Haldeman as Ed Jablonski (1980)
- Taylor Handley as Steve Jablonski (1980)
- Scott Vickaryous as John Harding ("John Doe") (1980)
- Cole Williams as Justin Bradley
- Rosemary Alexander as Mrs. Harding
- Hallock Beals as John Harding ("John Doe") (1968)
- Shiloh Fernandez as Valentino
- Jolene Hjerleid as Mrs. Jablonski (1980)
- Bill Schoesser as Vagrant
- Tom Wagner as Ed Jablonski (2006)
- John and Lilly mention and talk about the events of the season 2 finale The Woods, when Lilly shoots to death serial killer George Marks, almost being shot herself.
- Supertramp "Take the Long Way Home"
- Blondie "Atomic"
- Leah Siegel "Black Tile Room"
- Steve Miller Band "Winter Time"
- Depeche Mode "Precious"
- Messy Music "Long Cold Silence"
- Okkervil River "Black Sheep Boy #4"
- Closing Song: Lifehouse "You And Me"